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Cambridge Cardiovascular

 

Research

We develop Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) tools to assess atheromatous plaque inflammation and to perform stress analysis.

Publications

Key publications: 

Material properties of components in human carotid atherosclerotic plaques: A uniaxial extension study. Teng Z, Zhang Y, Huang Y, Feng J, Yuan J, Lu Q, Sutcliffe MP, Brown AJ, Jing Z, Gillard JH. Acta Biomater. 2014 Sep 6. pii: S1742-7061(14)00379-1. doi: 10.1016/j.actbio.2014.09.001. [Epub ahead of print]

Compounding local invariant features and global deformable geometry for medical image registration. Zhang J, Chen L, Wang X, Teng Z, Brown AJ, Gillard JH, Guan Q, Chen S. PLoS One. 2014 Aug 28;9(8):e105815.

Optimization of improved motion-sensitized driven-equilibrium (iMSDE) blood suppression for carotid artery wall imaging. Zhu C, Graves MJ, Yuan J, Sadat U, Gillard JH, Patterson AJ. J Cardiovasc Magn Reson. 2014 Aug 9;16:61.

Inflammation and neovascularization intertwined in atherosclerosis: imaging of structural and molecular imaging targets. Sadat U, Jaffer FA, van Zandvoort MA, Nicholls SJ, Ribatti D, Gillard JH. Circulation. 2014 Aug 26;130(9):786-94.

A pilot study exploring the mechanisms involved in the longitudinal propagation of acute aortic dissection through computational fluid dynamic analysis. Zhang Y, Lu Q, Feng J, Yu P, Zhang S, Teng Z, Gillard JH, Song R, Jing Z. Cardiology. 2014;128(2):220-5.

3D high-resolution contrast enhanced MRI of carotid atheroma--a technical update. Zhu C, Sadat U, Patterson AJ, Teng Z, Gillard JH, Graves MJ. Magn Reson Imaging. 2014 Jun;32(5):594-7.

Flow pattern analysis in a highly stenotic patient-specific carotid bifurcation model using a turbulence model. Li ZY, Tan FP, Soloperto G, Wood NB, Xu XY, Gillard JH. Comput Methods Biomech Biomed Engin. 2014 Feb 27. [Epub ahead of print]

Coronary plaque structural stress is associated with plaque composition and subtype and higher in acute coronary syndrome: the BEACON I (Biomechanical Evaluation of Atheromatous Coronary Arteries) study. Teng Z, Brown AJ, Calvert PA, Parker RA, Obaid DR, Huang Y, Hoole SP, West NE, Gillard JH, Bennett MR. Circ Cardiovasc Imaging. 2014 May;7(3):461-70.

The influence of computational strategy on prediction of mechanical stress in carotid atherosclerotic plaques: comparison of 2D structure-only, 3D structure-only, one-way and fully coupled fluid-structure interaction analyses. Huang Y, Teng Z, Sadat U, Graves MJ, Bennett MR, Gillard JH. J Biomech. 2014 Apr 11;47(6):1465-71.

Plaque hemorrhage in carotid artery disease: pathogenesis, clinical and biomechanical considerations. Teng Z, Sadat U, Brown AJ, Gillard JH. J Biomech. 2014 Mar 3;47(4):847-58.

Estimation of aortic pulse pressure using Fourier velocity encoded M-mode MR. Taviani V, Hickson SS, Hardy CJ, Patterson AJ, Young VE, McEniery CM, Wilkinson IB, Gillard JH, Graves MJ. J Magn Reson Imaging. 2014 Jan;39(1):85-93. doi: 10.1002/jmri.24109.

Professor of Neuroradiology
Professor Jonathan  Gillard

Affiliations

Classifications: 
Specialities: 
Person keywords: 
stroke
atherosclerosis
MRI
vascular imaging