skip to primary navigationskip to content
 

Professor Ken Smith

Keywords

clinical immunology ; autoimmunity

Key Publications

LeeJC, EspéliM, AndersonCA, LintermanMA, PocockJM, WilliamsNJ, RobertsR, ViatteS, FuB,   PeshuN, Tran TH, Nguyen HP, WesleyE, EdwardsC, AhmadT, MansfieldJC, GearryR, DunstanS,   Williams TS, BartonA, VinuesaCG, UK IBD Genetics Consortium, ParkesM, LyonsPA, SmithKGC.  Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway.  Cell 2013: 155(1):57-69. 

Marion Espéli, Menna R. Clatworthy, Susanne Bökers, Kate E. Lawlor, Antony J. Cutler, Frank Köntgen, Paul A. Lyons, Kenneth G. C. Smith. Analysis of a wild mouse Fcgr2b promoter variant reveals a novel role for FcgRIIb in the control of the germinal center and autoimmunity. J Exp Med, 2012  Nov 19;209(12):2307-19.

Lyons PA*, Rayner TF*, Trivedi S*, Holle JU, Watts RA, Jayne DRW, Baslund B, Brenchley P, Bruchfeld A, Chaudhry AN, Cohen Tervaert JW, Deloukas P, Feighery C, Gross WL, Guillevin L,Gunnarsson I, Harper L, Hrušková Z, Little MA, Martorana D, Neumann T, Ohlsson S, Padmanabhan S, Pusey CD, Salama AD, Sanders J-S F, Savage CO, Segelmark M, Stegeman CA, Tesař V, Vaglio A, Wieczorek S, Wilde B, Zwerina J, Rees AJ, Clayton DG and Smith KGC. Genetically Distinct Subsets within ANCA-Associated Vasculitis New England Journal of Medicine, 2012 Jul 19;367(3):214-23.
 
Linterman MA, Pierson W, Lee SK, Kallies A, Kawamoto S, Rayner TF, Srivastava M, Divekar DP, Beaton L, Hogan JJ, Fagarasan S, Liston A, Smith KGC* & Vinuesa CG*. Foxp3+ follicular regulatory T cells control the germinal center response. Nature Medicine, 2011
 
Lee JC, Lyons PA, McKinney EF, Sowerby JM, Carr EJ, Bredin F, Rickman HM, Ratlamwala H, Hatton A, Rayner TF, Parkes M, Smith KGC. Gene expression profiling of CD8+ T cells predicts prognosis in patients with Crohn disease and ulcerative colitis. Journal of Clinical Investigation, 2011; 121:4170-9.

 

McKinney EF, Lyons PA, Carr EJ, Hollis JL, Jayne DRW, Willcocks LC, Koukoulaki M, Hatton  A, MacAry PA, Brazma A, Chaudhry AN and Smith KGC.  A CD8 memory T cell transcription signature predicts prognosis in autoimmune diseases. Nature Medicine,  2010; in press.

Logo design by Dr Ana-Mishel Spiroski and Dr Sarah Morgan.

 

We connect cardiovascular researchers in Cambridge.

Please follow us on Twitter for local news about research, events, funding calls, and open positions.

For inquiries about our research or the website, please contact Dr Katja Kivinen.