I am interested in modelling and understanding the developmental biology of cardiac development. My focus is on inherited cardiovascular diseases and discovering new therapeutic potentials using a systems physiology perspective. Using an integrated platform of in silico computational modelling of the genome to in vitro hIPSC models to genome editing technology all technologies are applied to define possibilities in personalised medicine.
genome biology ; cardiac development
Shakur R, Moosa JM. et al. Gene selection for cancer classification with the help of bees. BMC Medical Genomics. 2016;9(Suppl 2):47.
Armstrong J, Shakur R et al. Artificial membrane binding proteins stimulate oxygenation of stem cells during tissue engineering of large cartilage constructs: Nature Communications. 2015 6;7405
Gulati A, Ismail TF , Shakur R et al. Clinical utility and prognostic value of left atrial volume assessment by cardiovascular magnetic resonance in non-ischaemic dilated cardiomyopathy. Eur J Heart Fail. 2013 Jun;15(6):660-70