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Cambridge Cardiovascular

 

Publications

Key publications: 

Varga TV, Sonestedt E, Shungin D, Koivula RW, Hallmans G, Escher SA, Barroso I, Nilsson P, Melander O, Orho-Melander M, Renström F, Franks PW: Genetic Determinants of Long-Term Changes in Blood Lipid Concentrations: 10-Year Follow-Up of the GLACIER Study. PLoS Genet. 2014 Jun 12;10(6):e1004388.

Dimas AS, Lagou V, Barker A, Knowles JW, Mägi R, Hivert MF, Benazzo A, Rybin D, Jackson AU, Stringham HM, Song C, Fischer-Rosinsky A, Boesgaard TW, Grarup N, Abbasi FA, Assimes TL, Hao K, Yang X, Lecoeur C, Barroso I, ..., Ingelsson E, McCarthy MI, Prokopenko I; MAGIC Investigators: Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity. Diabetes. 2014 Jun;63(6):2158-71.

Global Lipids Genetics Consortium, Willer CJ, Schmidt EM,... Barroso I, ..., Mohlke KL, Ingelsson E, Abecasis GR: Discovery and refinement of loci associated with lipid levels. Nat Genet. 2013 Nov;45(11):1274-83.

Do R, Willer CJ, Schmidt EM, Sengupta S,... Barroso I, ..., Abecasis GR, Daly MJ, Neale BM, Kathiresan S: Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet. 2013 Nov;45(11):1345-52.

Sabater-Lleal M, Huang J, Chasman D,... VTE Consortium; STROKE Consortium; Wellcome Trust Case Control Consortium 2 (WTCCC2); C4D Consortium; CARDIoGRAM Consortium, Wallaschofski H, Smith NL, Tregouet D, Ridker PM, Tang W, Strachan DP, Hamsten A, O'Donnell CJ: Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation. 2013 Sep 17;128(12):1310-24.

Voight BF, Kang HM, Ding J, Palmer CD, Sidore C, Chines PS, Burtt NP, Fuchsberger C, Li Y, Erdmann J, Frayling TM, Heid IM, Jackson AU, Johnson T, Kilpeläinen TO, Lindgren CM, Morris AP, Prokopenko I, Randall JC, Saxena R, Soranzo N, Speliotes EK, Teslovich TM, Wheeler E, Maguire J, Parkin M, Potter S, Rayner NW, Robertson N, Stirrups K, Winckler W, Sanna S, Mulas A, Nagaraja R, Cucca F, Barroso I, Deloukas P, Loos RJ, Kathiresan S, Munroe PB, Newton-Cheh C, Pfeufer A, Samani NJ, Schunkert H, Hirschhorn JN, Altshuler D, McCarthy MI, Abecasis GR, Boehnke M: The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits. PLoS Genet. 2012;8(8):e1002793.

IL6R Genetics Consortium Emerging Risk Factors Collaboration, Sarwar N, Butterworth AS,... Ouwehand WH, Samani NJ, Kaptoge S, Di Angelantonio E, Harari O, Danesh J: Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet. 2012 Mar 31;379(9822):1205-13.

International Consortium for Blood Pressure Genome-Wide Association Studies, Ehret GB, Munroe PB, Rice KM,... Barroso I, ... Newton-Cheh C, Levy D, Caulfield MJ, Johnson T: Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011 Sep 11;478(7367):103-9.

Wain LV, Verwoert GC, O'Reilly PF, Shi G,... Barroso I, ... Rao DC, Tobin MD, Elliott P, van Duijn CM: Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet. 2011 Sep 11;43(10):1005-11.

Now at University of Exeter
Dr Ines  Barroso

Affiliations