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Cambridge Cardiovascular

 

Research

MR JAMES COOPER HAS LEFT CAMBRIDGE AND WORKS NOW IN PROF CHANDRAN'S GROUP AT THE UNIVERSITY OF EDINBURGH

Prior to my current role, I worked at Wellcome Trust Sanger Institute as an Advanced Research Assistant, expanding and maintaining the International Knockout Mouse Consortium (IKMC) miRNA Knockout Resource (miRKO), with focus on high-throughput vector construction, mouse ES cell culture, targeting, and genotyping.

I moved to the University in March 2014, to provide core support to the newly established BHF Oxbridge Centre of Regenerative Medicine. My primary role has been in Genome Engineering with focus on editing/transgenics using CRISPR/Cas9 - projects I have been involved with so far have been listed below:

 

Publications

Key publications: 

Optimized inducible shRNA and CRISPR/Cas9 platforms for in vitro studies of human development using hPSCs. Bertero A, Pawlowski M, Ortmann D, Snijders K, Yiangou L, Cardoso de Brito M, Brown S, Bernard WG, Cooper JD, Giacomelli E, Gambardella L, Hannan NR, Iyer D, Sampaziotis F, Serrano F, Zonneveld MC, Sinha S, Kotter M, Vallier L. Development. 2016 Dec 1;143(23):4405-4418.

 

Senior Research Technician
 James  Cooper

Affiliations

Classifications: 
Person keywords: 
transfection
gene expression profiling
stem cells
mammalian cell culture
genotyping
gene targeting
vector construction
CRISPR-Cas9
regenerative medicine