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Cambridge Cardiovascular


School of Clinical Medicine

Applications are invited to join a dynamic team led by Dr Sanjay Sinha, working to develop a novel cardiac 'patch' for the treatment of impaired cardiac function after myocardial injury. The focus of this exciting bio-engineering project will be on ways to incorporate human embryonic stem cell-derived cells onto microporus collagen scaffolds coated with specific cell attachment peptides, to optimise cell survival, function and vascularisation. The successful applicant will work as part of a larger ongoing bio-engineering consortium together with colleagues in Biochemistry (Prof Richard Farndale), Materials Science (Profs Serena Best & Ruth Cameron) and Experimental Medicine (Dr Thomas Krieg) to develop and generate the next generation of vascularised and functional cardiac patches.

We have recently established novel in vitro systems using human ES and iPS cells in which embryonic origin-specific smooth muscle cells may be generated (Cheung et al Nature Biotech 2012 & Iyer et al Development 2015) and which provide an excellent platform for translational studies in cardiovascular regenerative medicine.

You will have a PhD with an extensive background in cell and molecular biology and a strong publication record. It is essential that you have excellent communication and organisational skills and the ability to work collaboratively. Prior experience with human ES/iPS cells and in bio-engineering will be advantageous.

Informal enquiries to Dr Sanjay Sinha ( are strongly encouraged.

Fixed-term: The funds for this post are available until 30 September 2019 in the first instance.

The closing date for this vacancy is Wednesday 25 November 2015.

Interviews are likely to take place on Tuesday 15 December 2015 and Friday 18 December 2015.

More information and instructions to apply online can be found on the University of Cambridge jobs website.

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