Dr Daniel Gaffney
- CDF Group Leader (Sanger Institute)
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Research
Statistical and regulatory genomics in human induced pluripotent stem cells
My research focuses on gene regulation in human cells through combining methods in statistical genetics and comparative genomics with high-throughput experimental techniques, such as ChIP-seq and DNaseI-seq.
My group uses naturally occurring human genetic variation as a model system to test hypotheses about gene regulation. we are also interested in developing evolutionary models of gene regulation to understand how changes at the molecular level drive gene expression divergence between species.