skip to content

Cambridge Cardiovascular


MED-KIT: Making use of Ex-situ Donated hearts for Knowledge and Innovation of Therapeutics


A series of workshops organised by researchers from Cambridge Cardiovascular. We will bring together heart transplant recipients, family members of donors, transplant professionals and patients on the waiting list with academics working on heart health to share a range of views on using recipients’ explanted organs in research.  

Heart failure affects over 37 million patients worldwide, carries a 5-year mortality of 50% and costs £2bn annually in the UK. Current medical therapies aim to manage the cause and relieve symptoms; however, they do not reverse the underlying pathophysiological processes. We need to develop therapeutics that are effective in reversing these processes. Ex-Situ Heart Perfusion (ESHP) offers a powerful tool by which novel therapeutics can be tested on human hearts from transplant recipients or from donor hearts that cannot be used for transplant. We believe that cardiovascular research using this approach can bring widespread benefits to future patients. Gathering views from a range of stakeholders is vital to support mutual understanding and decisions on the ethics of research using human tissues.


Big Biology Day

The Cambridge Big Biology Day takes place every October at Hills Road Sixth Form College, and is open to people of all ages with an interest in Biology and Science. We attend to meet and hopefully inspire the next generation of researchers. Please contact Jane Sugars or Denise Hatherly if you would like to volunteer.

A big thank you to Deeti Shetty from the Sinha Lab and Jack Palmer currently on rotation at the Wellcome Sanger Institute for their help this year.


Cambridge Festival

Please see our dedicated Festival page.


Videos from our Researchers

Dr Sanjay Sinha introduces us to the development of 'cardiac patches'. The project aims to grow human heart muscle tissue in the lab to replace injured tissue after a heart attack, and is one of the flagship projects of the BHF Centre of Regenerative Medicine. The work is an interdisciplinary collaboration with Prof Ruth Cameron and Prof Serena Best in Materials Science, Prof Richard Farndale in Biochemistry, and Dr Thomas Krieg in Experimental Medicine:


To complement the story about cardiac patches, Cambridge Centre for Medical Materials co-led by Prof Ruth Cameron and Prof Serena Best have published a short introduction to their research, especially around the use of collagen scaffolds to direct cell growth:


NIHR Cambridge Biomedical Research Centre has published a short introduction to cardiovascular and respiratory disease research featuring Prof Nick Morrell:


In 2017, the University of Cambridge published a compilation of "The Future of Medicine", including a clip about the development of cardiac patches by Dr Sanjay Sinha and colleagues:

In 2015, the British Heart Foundation awarded Dr Geoff Moggridge a special project grant to test new heart valve material that may revolutionise valve replacements in humans:

In 2014, the British Heart Foundation interviewed Dr Sanjay Sinha, Dr Alessandra Granata and Dr Johannes Bargehr about ground-breaking cardiovascular research done in Cambridge:

There is also a longer version of this video including personal stories shared by patients:

Cambridge Cardiovascular logo - transparent

We connect cardiovascular researchers in Cambridge and beyond.

For inquiries about our research, please contact Dr Jane Sugars

For enquiries about our website or joining Cambridge Cardiovascular, please contact Denise Hatherly

Find us on LinkedIn


Follow us on X

Please follow us here on X for local news about research, events, funding calls, and open positions.

You must be logged into X to see our feed here:

Our Newsletter

Click on the image below for previous Newsletters and for our Email sign up form


Find us on YouTube