When Symptoms Don't Stop
Jan 22, 2021
Treating those most severely affected by COVID-19 has necessarily taken priority during the pandemic. But could long COVID be the next wave of the crisis?
SIRT6 Protects Smooth Muscle Cells from Senescence and Reduces Atherosclerosis
Dec 23, 2020
SIRT6 protein expression is reduced in human and mouse plaque VSMCs and is positively regulated by CHIP. SIRT6 regulates telomere maintenance and VSMC lifespan, and inhibits atherogenesis, all dependent on its deacetylase activity. Our data shows that endogenous SIRT6 deacetylase is an important and unrecognized inhibitor of VSMC senescence and atherosclerosis.
Policy, Scientific Advocacy, and Combatting Obesity- workshop outcome
Dec 23, 2020
The United Kingdom is one of the most obese countries in the world, with more than two-thirds of adults overweight. The covid-19 pandemic has brought increased attention to the obesity epidemic, as being overweight increases the risk of hospitalization or death due to the virus. With this context in mind, CSaP convened an expert panel and a group of early career researchers from the Cambridge Metabolic Network and the Cardiovascular Interdisciplinary Research Centre to explore the role of scientific advice and advocacy in responding to the UK's obesity epidemic.
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