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Dr Ammara Usman

Dr Ammara Usman

PhD candidate

Honorary Clinical Fellow


Departments and Institutes

Department of Radiology:

Research Interests

We develop Magnetic Resonance Imaging (MRI) tools to assess atheromatous plaque inflammation and to perform biomechanical stress analysis. I have special interest in imaging functional activity of the carotid atheroma using Dynamic contrast enhanced and USPIO-enhanced MR imaging.  During my PhD, I investigate the utility of new member of ultrasmall superparamagnetic particle of iron oxide (USPIO) group called Ferumoxytol to highlight the risky spots (inflammation) in the carotid atheroma by Ferumoxytol-enhanced MR imaging.

Keywords

DCE MRI: Nano particle ; atherosclerosis ; stroke ; MRI ; USPIO

Key Publications

Usman A, Yuan J, Patterson AJ, Graves MJ, Varty K, Sadat U, Gillard JH, Neovascularization in Vertebral Artery Atheroma-A Dynamic Contrast-Enhanced Magnetic Resonance Imaging-Based Comparative Study in Patients with Symptomatic and Asymptomatic Carotid Artery Disease, J Stroke Cerebrovasc Dis,2018

Usman A, Patterson AJ, Sadat U, Gillard JH, et al, Assessment of Carotid Plaque Inflammation in Diabetic and Nondiabetic Patients-An Exploratory Ultrasmall Superparamagnetic Iron Oxide-Enhanced Magnetic Resonance Imaging Study, J Stroke Cerebrovasc Dis, 2017

Usman A, Sadat U, Teng Z, Gillard JH et al, Magnetic Resonance Imaging-Based Assessment of Carotid Atheroma: a Comparative Study of Patients with and without Coronary Artery Disease, J Stroke Cerebrovasc Dis, Oct 2016.

Usman A, Sadat U, Patterson AJ, Gillard JH et al, Use of ultrasmall superparamagnetic iron oxide particles for imaging carotid atherosclerosis, Nanomedicine (Lond), Sep 2015

Usman A, Sadat U, Graves MJ, Gillard JH et al, Magnetic resonance imaging of atherothrombotic plaques, J Clin Neurosci, Aug 2015

Usman A, Ribatti D, Sadat U, Gillard JH, et al, From Lipid Retention to Immune Mediate Inflammation and Associated Angiogenesis in the Pathogenesis of Atherosclerosis, J Atheroscler Thromb, Jul 2015.

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