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Dr Mark Toshner

Dr Mark Toshner

Director of Translational Biomedical Research MPhil

Honorary Consultant Papworth Hospital NHS Trust

Honorary Consultant Cambridge University Hospitals NHS Trust

Office Phone: 01223 762007

Departments and Institutes

Papworth Hospital:

Research Interests

Dr Toshner undertook a British Heart Foundation Research Training Fellowship in Cambridge in 2007 where he trained in cell and molecular mechanisms of endothelial dysfunction in pulmonary hypertension. He was appointed to a Wellcome/ NIHR Clinical Lecturer in 2010. He is the current University Lecturer in Translational Respiratory Research and his group is interested in translational and experimental research in pulmonary vascular diseases. He is currently the Chief-Investigator of the Transform-UK trial, the first investigator-led multicentre trial to involve all 7 specialist centres in the UK. He is leading an international genotyping/ phenotyping collaboration in chronic thromboembolic pulmonary hypertension and  has close ties to the Pulmonary Vascular Diseases Unit in Royal Papworth Hospital. His research group is focused on preclinical target identification and early phase trials in pulmonary vascular diseases.

The major themes of the group are-

  • Genetic susceptibility to pulmonary hypertension
  • The pathobiology of chronic thromboembolic pulmonary hypertension
  • Novel early phase drug development in pulmonary hypertension


Dr Toshner is Director of the MPhil in Translational Biomedical Research and stem lead for all Clinical School taught MPhils.






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