Available projects have been divided into three subgroups depending on their focus: Vascular Biology; Stem Cell and Developmental Biology; and Population Health and Genomics.
Cardiovascular Biology
| Principle Investigator | Research Field |
|---|---|
| Prof Martin Bennett | Control of vascular smooth muscle cell apoptosis and cell senescence |
| Prof Murray Clarke | Pathways linking cell death and inflammation in vascular disease |
| Prof Anthony Davenport | Role of G-protein coupled receptors and biased signalling in the human cardiovascular system |
| Dr Matthew Harper | Regulation of thrombosis in response to vascular injury |
| Prof Thomas Krieg | Cardiovascular Ischaemia/Reperfusion Injury |
| Dr Wei Li | Regulation of bone morphogenetic protein signaling in vascular endothelial cells |
| Dr Xuan Li | Novel players linking inflammasome activation to cardiovascular disease |
| Prof Ziad Mallat | Immune mechanisms in cardiovascular disease |
| Prof Michael Murphy |
Mitochondrial processes contributing to ischemia-reperfusion injury |
| Dr Meritxell Nus | Metabolic pathways to Tfh differentiation in atherosclerosis |
| Dr Andrew Sage | Adaptive Immune responses and Atherosclerosis |
| Prof Antonio Vidal-Puig | Molecular Mechanisms of Energy Balance |
| Dr Ana Vujic | Role of exercise in mitigating heart failure symptoms |
| Dr Emma Yu | Regulation, consequences and treatment of mitochondrial dysfunction in atherosclerosis |
Stem Cell and Developmental Biology
| Principle Investigator | Research Field |
|---|---|
| Dr Cedric Ghevaert | Platelet production from pluripotent stem cells for disease modelling and cellular therapy |
| Prof Dino Giussani | Developmental Origins of Heart Disease |
| Dr Alessandra Granata |
iPSC modelling of cerebrovascular diseases |
| Dr Helle Jørgensen | Regulation of cell plasticity in cardiovascular development and disease |
| Prof Susan Ozanne | Developmental programming of cardiovascular and metabolic disease |
| Prof Sanjay Sinha | Vascular smooth muscle cell development and disease |
| Dr Richard Tyser |
Emergence of form and function during early heart development |
Genetics and Genomics
| Principle Investigator | Research Field |
|---|---|
| Prof Sarah Teichmann | Systems biology, single cell genomics and computational biology |
