RNA editing by ADAR1 in pulmonary hypertension - Dr Roger Thompson, Sheffield
What have Pattern Recognition Receptors and Inflammasomes ever done for us? - Professor Clare Bryant, Cambridge
Roger is senior lecturer in respiratory medicine at the University of Sheffield, based in the Royal Hallamshire Hospital’s pulmonary vascular disease unit. He has had a broad range of research interests including altitude hypoxia and neutrophilic inflammation with current projects investigating post-COVID breathlessness and pulmonary hypertension using multinuclear magnetic resonance imaging. This talk will describe work exploring whether the sensing and regulation of double-stranded RNA is involved in pathological pulmonary vascular remodelling in pulmonary hypertension.
Clare Bryant is Professor of Innate Immunity in the Departments of Medicine and Veterinary Medicine. She graduated in Biochemistry and Physiology in Southampton University before training as a vet at the Royal Veterinary College in London. She was funded by the Wellcome Trust for her PhD (in London) before moving to the William Harvey Research Institute for 4 years as a Wellcome postdoctoral fellow. She then moved to Cambridge as a Wellcome Trust Career Development Fellow where she is now Professor of Innate Immunity. She has been on secondments in Genentech and GSK, has extensive collaborations with many pharmaceutical companies, is on the scientific advisory board of several biotech companies, has a drug discovery project with Apollo Therapeutics and helped found the natural product company Polypharmakos. During the COVID-19 pandemic she founded, and still runs, the Inflammazoom international seminar series. She was elected as a Fellow of the British Pharmacology Society in 2018 and as a Fellow of the American Academy of Microbiology in 2023.
