News

Platelet function modified by megakaryocyte super enhancer sequence variation

3 August 2017

A collaboration between the University of Cambridge, Wellcome Trust Sanger Institute, and Babraham Institute, has shed light on the mechanism behind the association of genetic variation and platelet function. Led by Dr Mattia Frontini , the researchers have shown that common genetic variants associated with platelet traits...

€3.2M EU Horizon 2020 grant for in vitro platelet production

3 August 2017

Dr Cedric Ghevaert has been awarded a €3.2M EU Horizon 2020 grant in collaboration with Alessandra Balduini (Pavia) and Hana Raslova (Paris). Thei project called SilkFUSIOn will produce platelets in vitro on silk-based scaffolds using the teams' existing expertise in induced pluripotent stem cell (iPSC) technology. The...

Vice Chancellor's Impact Award to Prof Nick Morrell

17 July 2017

Prof Nick Morrell was among the winners of this year's Vice-Chancellor's Impact Awards that were announced at the prize ceremony on 13 July. Severe high blood pressure in the lungs, known as idiopathic pulmonary arterial hypertension (PAH), is a rare disease that affects approximately 1,000 people in the UK. PAH usually...

£1.3M BHF Programme Grant to support research into aortic aneurysms

9 June 2017

The BHF has awarded Dr Sanjay Sinha and Dr Paul Bertone a £1,270,000 programme grant over five years to identify new therapeutic strategies for genetically-triggered thoracic aortic aneurysm syndromes (Marfan, Loeys-Dietz, Ehlers-Danlos and ACTA2). Although rupture or dissection of these aneurysms can have catastrophic...

Join the new BHF alumni programme

8 June 2017

The BHF is launching a free membership programme to support the community of past and present researchers throughout the world. Everyone who has received funding from the BHF or is currently supported by them is eligible to join the new network. More information about the programme and joining instructions can be found on...

British Science Association Media Fellowship

24 May 2017

Dr James Rudd has been awarded a British Science Association (BSA) Media Fellowship . The BSA awards up to ten Fellowships annually to active scientists, clinicians, and engineers. Fellows are placed into mainstream media organisations for 2-6 week secondments to give them an opportunity to gain an in-depth understanding...

Fifteen new risk loci for coronary artery disease

24 May 2017

Dr Joanna Howson , Dr Adam Butterworth , Prof John Danesh , and others have discovered 15 new risk loci for coronary artery disease in work published in Nature Genetics . Coronary artery disease (CAD) is a leading cause of morbidity and mortality worldwide. Although tens of genomic regions have been associated with CAD so...

Myosin VI role in the heart muscle cell gap junction homeostasis

18 May 2017

Dr Folma Buss and others have identified a new role for myosin VI in the construction and maintenance of gap junctions between cardiomyocytes. Cardiac function depends on the precise transmission of electrical activity throughout the heart muscle, and disturbances to this highly coordinated process are the hallmark of...

Marginal zone B cell role in immune homeostasis in response to high cholesterol diet

2 May 2017

Prof Ziad Mallat , Dr Meritxell Nus , Dr Andrew Sage , and others have discovered a new role for margical zone B cells in immune homeostasis in response to high cholesterol diet. Marginal zone B cells belong to the B2 subset of B cells that have previously been thought to be atherogenic. However, the specific role of...

£1.8M MRC grant to study low dose IL-2 in patients with recent acute coronary syndrome

4 April 2017

MRC has awarded Prof Ziad Mallat a project grant worth £1.8M to study the effects of low dose IL-2 in patients with recent acute coronary syndrome . Cardiovascular diseases (CVD) are the leading cause of mortality in the World. CVD mostly result from atherosclerosis - the build-up of fatty plaques in the walls of our...

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Platelet function modified by megakaryocyte super enhancer sequence variation

€3.2M EU Horizon 2020 grant for in vitro platelet production

Vice Chancellor's Impact Award to Prof Nick Morrell

£1.3M BHF Programme Grant to support research into aortic aneurysms

Join the new BHF alumni programme

British Science Association Media Fellowship

Fifteen new risk loci for coronary artery disease

Myosin VI role in the heart muscle cell gap junction homeostasis

Marginal zone B cell role in immune homeostasis in response to high cholesterol diet

£1.8M MRC grant to study low dose IL-2 in patients with recent acute coronary syndrome

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