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Dr James Fraser

Dr James Fraser

University Lecturer in Circulatory Physiology

Director of Studies in Medicine, Gonville and Caius College

Office Phone: 01223 333815

Research Interests

I aim to improve the diagnosis and treatment of cardiac arrhythmias. My group’s current focus is on genetic conditions which predispose to sudden death. We aim to use what we learn from these conditions to better understand common conditions including atrial fibrillation. We use a combination of experimental work and computer modelling to fully understand the complex mechanisms underlying electrical activity in the heart in health and disease.


cardiac arrhythmia ; atrial fibrillation ; computer modelling ; cardiac electrophysiology


  • Sudden cardiac death
  • Atrial fibrillation
  • Catecholaminergic polymorphic ventricular tachycardia (CPVT)
  • Brugada syndrome


  • Langendorff perfusion
  • Ca2+ imaging and intracellular electrode techniques

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