skip to primary navigationskip to content

Professor Jonathan Mant

Professor Jonathan Mant

Professor of Primary Care Research

Head of Primary Care Unit

Research themes

Population Sciences:

Research Interests

Cardiovascular Disease in Primary Care Settings

My research focuses on stroke prevention and treatment in primary care settings. I am currently the principal investigator on two programme grants: the Stroke Association/British Heart Foundation funded preventive role of a polypill and NIHR funded developing primary care stroke services.


public health ; public policy ; stroke ; heart failure

Key Publications

Recent publications are listed on PubMed.

Different systolic blood pressure targets for people with history of stroke or transient ischaemic attack: PAST-BP (Prevention After Stroke-Blood Pressure) randomised controlled trial. Mant J, McManus RJ, Roalfe A, Fletcher K, Taylor CJ, Martin U, Virdee S, Greenfield S, Hobbs FD. BMJ. 2016 Feb 24;352:i708. doi: 10.1136/bmj.i708.

The diagnostic accuracy of the natriuretic peptides in heart failure: systematic review and diagnostic meta-analysis in the acute care setting. Roberts E, Ludman AJ, Dworzynski K, Al-Mohammad A, Cowie MR, McMurray JJ, Mant J; NICE Guideline Development Group for Acute Heart Failure. BMJ. 2015 Mar 4;350:h910.

Ethnicity and Differences Between Clinic and Ambulatory Blood Pressure Measurements. Martin U, Haque MS, Wood S, Greenfield SM, Gill PS, Mant J, Mohammed MA, Heer G, Johal A, Kaur R, Schwartz C, McManus RJ. Am J Hypertens. 2014 Nov 13.

Diagnosing and managing acute heart failure in adults: summary of NICE guidance. Dworzynski K, Roberts E, Ludman A, Mant J; Guideline Development Group. BMJ. 2014 Oct 8;349:g5695.

Prevalence and costs of treating uncomplicated stage 1 hypertension in primary care: a cross-sectional analysis. Sheppard JP, Fletcher K, McManus RJ, Mant J. Br J Gen Pract. 2014 Oct;64(627):e641-8.

The INTERVAL trial to determine whether intervals between blood donations can be safely and acceptably decreased to optimise blood supply: study protocol for a randomised controlled trial. Moore C, Sambrook J, Walker M, Tolkien Z, Kaptoge S, Allen D, Mehenny S, Mant J, Di Angelantonio E, Thompson SG, Ouwehand W, Roberts DJ, Danesh J. Trials. 2014 Sep 17;15:363.

Effect of self-monitoring and medication self-titration on systolic blood pressure in hypertensive patients at high risk of cardiovascular disease: the TASMIN-SR randomized clinical trial. McManus RJ, Mant J, Haque MS, Bray EP, Bryan S, Greenfield SM, Jones MI, Jowett S, Little P, Penaloza C, Schwartz C, Shackleford H, Shovelton C, Varghese J, Williams B, Hobbs FD, Gooding T, Morrey I, Fisher C, Buckley D. JAMA. 2014 Aug 27;312(8):799-808.

Predicting out-of-office blood pressure level using repeated measurements in the clinic: an observational cohort study. Sheppard JP, Holder R, Nichols L, Bray E, Hobbs FD, Mant J, Little P, Williams B, Greenfield S, McManus RJ. J Hypertens. 2014 Nov;32(11):2171-8

Medication taking in coronary artery disease: a systematic review and qualitative synthesis. Rashid MA, Edwards D, Walter FM, Mant J. Ann Fam Med. 2014 May-Jun;12(3):224-32.

Warfarin versus aspirin for prevention of cognitive decline in atrial fibrillation: randomized controlled trial (Birmingham Atrial Fibrillation Treatment of the Aged Study). Mavaddat N, Roalfe A, Fletcher K, Lip GY, Hobbs FD, Fitzmaurice D, Mant J. Stroke. 2014 May;45(5):1381-6.

Cost-effectiveness of optimizing acute stroke care services for thrombolysis. Penaloza-Ramos MC, Sheppard JP, Jowett S, Barton P, Mant J, Quinn T, Mellor RM, Sims D, Sandler D, McManus RJ; Birmingham and Black Country Collaborations for Leadership in Applied Health Research and Care Investigators. Stroke. 2014 Feb;45(2):553-62.

More publications available through PubMed.

Cambridge Cardiovascular logo - transparent

Logo design by Dr Ana-Mishel Spiroski and Dr Sarah Morgan.


We connect cardiovascular researchers in Cambridge.

Please follow us on Twitter for local news about research, events, funding calls, and open positions.

For inquiries about our research or the website, please contact Dr Katja Kivinen.