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Professor Sylvia Richardson

Research themes

Population Sciences:


network modelling ; high-dimensional data ; gene regulation ; gene-environment interactions

Key Publications

Transcriptional diversity during lineage commitment of human blood progenitors. Chen L, Kostadima M, Martens JH, Canu G, Garcia SP, Turro E, Downes K, Macaulay IC, Bielczyk-Maczynska E, Coe S, Farrow S, Poudel P, Burden F, Jansen SB, Astle WJ, Attwood A, Bariana T, de Bono B, Breschi A, Chambers JC; BRIDGE Consortium, Choudry FA, Clarke L, Coupland P, van der Ent M, Erber WN, Jansen JH, Favier R, Fenech ME, Foad N, Freson K, van Geet C, Gomez K, Guigo R, Hampshire D, Kelly AM, Kerstens HH, Kooner JS, Laffan M, Lentaigne C, Labalette C, Martin T, Meacham S, Mumford A, Nürnberg S, Palumbo E, van der Reijden BA, Richardson D, Sammut SJ, Slodkowicz G, Tamuri AU, Vasquez L, Voss K, Watt S, Westbury S, Flicek P, Loos R, Goldman N, Bertone P, Read RJ, Richardson S, Cvejic A, Soranzo N, Ouwehand WH, Stunnenberg HG, Frontini M, Rendon A. Science. 2014 Sep 26;345(6204):1251033.

Identifying cell types from spatially referenced single-cell expression datasets. Pettit JB, Tomer R, Achim K, Richardson S, Azizi L, Marioni J. PLoS Comput Biol. 2014 Sep 25;10(9):e1003824.

Blood pressure differences associated with Optimal Macronutrient Intake Trial for Heart Health (OMNIHEART)-like diet compared with a typical American Diet. Molitor J, Brown IJ, Chan Q, Papathomas M, Liverani S, Molitor N, Richardson S, Van Horn L, Daviglus ML, Dyer A, Stamler J, Elliott P; INTERMAP Research Group. Hypertension. 2014 Dec;64(6):1198-204.

Weibull regression with Bayesian variable selection to identify prognostic tumour markers of breast cancer survival. Newcombe P, Raza Ali H, Blows F, Provenzano E, Pharoah P, Caldas C, Richardson S. Stat Methods Med Res. 2014 Sep 4.

A semi-parametric approach to estimate risk functions associated with multi-dimensional exposure profiles: application to smoking and lung cancer. Hastie DI, Liverani S, Azizi L, Richardson S, Stücker I. BMC Med Res Methodol. 2013 Oct 23;13:129.

GUESS-ing polygenic associations with multiple phenotypes using a GPU-based evolutionary stochastic search algorithm. Bottolo L, Chadeau-Hyam M, Hastie DI, Zeller T, Liquet B, Newcombe P, Yengo L, Wild PS, Schillert A, Ziegler A, Nielsen SF, Butterworth AS, Ho WK, Castagné R, Munzel T, Tregouet D, Falchi M, Cambien F, Nordestgaard BG, Fumeron F, Tybjærg-Hansen A, Froguel P, Danesh J, Petretto E, Blankenberg S, Tiret L, Richardson S. PLoS Genet. 2013;9(8):e1003657.

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