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Cambridge Cardiovascular



Identification of 'high-risk' coronary plaques; Intravascular Imaging; Translational research in interventional cardiology


Key publications: 


  1. Brown AJ, Teng Z, Calvert PA, Rajani NK, Hennessy O, Nerlekar N, Obaid DR, Costopoulos C, Huang Y, Hoole SP, Goddard M, West NE, Gillard JH, Bennett MR. Plaque Structural Stress Estimations Improve Prediction of Future Major Adverse Cardiovascular Events After Intracoronary Imaging. Circ Cardiovasc Imaging. 2016  Jun;9(6). pii: e004172. doi: 10.1161/CIRCIMAGING.115.004172. PubMed PMID: 27307548. 

  2. Farag M, Costopoulos C, Gorog DA, Prasad A, Srinivasan M. Treatment of calcified coronary artery lesions. Expert Rev Cardiovasc Ther. 2016 Jun;14(6):683-90. doi: 10.1586/14779072.2016.1159513. PubMed PMID: 26924773.

  3. Costopoulos C, Crowson MC, Brown AJ, Braganza DM, Bennett MR, Hoole SP, West NE. Mid-term clinical outcomes of ABSORB bioresorbable vascular scaffold implantation in a real-world population: A single-center experience. Cardiovasc Revasc Med. 2015 Dec;16(8):461-4. doi: 10.1016/j.carrev.2015.08.003. PubMed PMID: 26440767.

  4. Brown AJ, Obaid DR, Costopoulos C, Parker RA, Calvert PA, Teng Z, Hoole SP, West NE, Goddard M, Bennett MR. Direct Comparison of Virtual-Histology Intravascular Ultrasound and Optical Coherence Tomography Imaging for Identification of Thin-Cap Fibroatheroma. Circ Cardiovasc Imaging. 2015 Oct;8(10):e003487. doi: 10.1161/CIRCIMAGING.115.003487. PubMed PMID: 26429760; PubMed Central PMCID: PMC4596008

  5. Costopoulos C, Brown AJ, Teng Z, Hoole SP, West NE, Samady H, Bennett MR. Intravascular ultrasound and optical coherence tomography imaging of coronary atherosclerosis. Int J Cardiovasc Imaging. 2016 Jan;32(1):189-200. doi: 10.1007/s10554-015-0701-3. PubMed PMID: 26153522

  6. Mitomo S, Naganuma T, Takagi K, Costopoulos C, Nakamura S, Hozawa K, Kurita N, Tahara S, Ishiguro H, Nakamura S. Comparison between Plain Old Balloon Angioplasty and Drug-Eluting Stent Implantation for the Treatment of Stent Fracture. J Interv Cardiol. 2015 Aug;28(4):365-73. doi: 10.1111/joic.12215. PubMed PMID: 26138831

  7. Yousef A, Simard T, Webb J, Rodés-Cabau J, Costopoulos C, Kochman J, Hernández-Garcia JM, Chiam PT, Welsh RC, Wijeysundera HC, García E, Ribeiro HB, Latib A, Huczek Z, Shanks M, Testa L, Farkouh ME, Dvir D, Velianou JL, Lam BK, Pourdjabbar A, Glover C, Hibbert B, Labinaz M. Transcatheter aortic valve implantation in patients with bicuspid aortic valve: A patient level multi-center analysis. Int J Cardiol. 2015;189:282-8. doi: 10.1016/j.ijcard.2015.04.066. PubMed PMID: 25910593

  8. Costopoulos C, Sutaria N, Ariff B, Fertleman M, Malik I, Mikhail GW. Balloon aortic valvuloplasty as a treatment option in the era of transcatheter aortic valve implantation. Expert Rev Cardiovasc Ther. 2015 May;13(5):457-60. doi: 10.1586/14779072.2015.1036742. PubMed PMID: 25865236

  9. Ielasi A, Latib A, Sacco FM, Costopoulos C, Figini F, Grimaldi A, Naim C, Maisano F, Chieffo A, Montorfano M, Alfieri O, Colombo A. Impact and natural history of postprocedural aortic regurgitation on early and midterm mortality following transcatheter aortic valve implantation in high-risk patients with severe aortic stenosis. J Cardiovasc Med (Hagerstown). 2015 Apr;16(4):286-95. doi: 10.2459/JCM.0000000000000249. PubMed PMID: 25643194.


Clinical Research Fellow
Dr Charis  Costopoulos