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Cambridge Cardiovascular

 
Read more at: Dr Rouchelle Sriranjan Rothwell

Dr Rouchelle Sriranjan Rothwell

NIHR Clinical Lecturer in Cardiology (University of Cambridge)

Interventional Cardiology SpR (Royal Papworth Hospital)


Read more at: Dr Benn Jessney

Dr Benn Jessney

Clinical Research Associate / Cardiology Specialty Registrar




Read more at: Dr Tian Zhao

Dr Tian Zhao

Journal articles

2023

  • Zhao, TX. and Mallat, Z., 2023. Will gazing into the single-cell multiome illuminate cardiovascular drug development? Nat Cardiovasc Res, v. 2
    Doi: http://doi.org/10.1038/s44161-022-00209-3
  • 2022

  • Zhao, TX., Aetesam-Ur-Rahman, M., Sage, AP., Victor, S., Kurian, R., Fielding, S., Ait-Oufella, H., Chiu, Y-D., Binder, CJ., Mckie, M., Hoole, SP. and Mallat, Z., 2022. Rituximab in patients with acute ST-elevation myocardial infarction: an experimental medicine safety study. Cardiovasc Res, v. 118
    Doi: http://doi.org/10.1093/cvr/cvab113
  • Zhao, TX., Sriranjan, RS., Tuong, ZK., Lu, Y., Sage, AP., Nus, M., Hubsch, A., Kaloyirou, F., Vamvaka, E., Helmy, J., Kostapanos, M., Jalaludeen, N., Klatzmann, D., Tedgui, A., Rudd, JHF., Horton, SJ., Huntly, BJP., Hoole, SP., Bond, SP., Clatworthy, MR., Cheriyan, J. and Mallat, Z., 2022. Regulatory T-Cell Response to Low-Dose Interleukin-2 in Ischemic Heart Disease. NEJM Evid, v. 1
    Doi: 10.1056/EVIDoa2100009
  • Zhao, TX., Sriranjan, RS., Tuong, ZK., Lu, Y., Sage, AP., Nus, M., Hubsch, A., Kaloyirou, F., Vamvaka, E., Helmy, J., Kostapanos, M., Jalaludeen, N., Klatzmann, D., Tedgui, A., Rudd, JHF., Horton, SJ., Huntly, BJP., Hoole, SP., Bond, SP., Clatworthy, MR., Cheriyan, J. and Mallat, Z., 2022. Regulatory T-Cell Response to Low-Dose Interleukin-2 in Ischemic Heart Disease NEJM Evidence, v. 1
    Doi: 10.1056/evidoa2100009
  • 2021

  • Aetesam-Ur-Rahman, M., Giblett, JP., Khialani, B., Kyranis, S., Clarke, SJ., Zhao, TX., Braganza, DM., Clarke, SC., West, NEJ., Bennett, MR. and Hoole, SP., 2021. GLP-1 vasodilatation in humans with coronary artery disease is not adenosine mediated. BMC Cardiovasc Disord, v. 21
    Doi: http://doi.org/10.1186/s12872-021-02030-5
  • Yu, X., Newland, SA., Zhao, TX., Lu, Y., Sage, AS., Sun, Y., Sriranjan, RS., Ma, MKL., Lam, BYH., Nus, M., Harrison, JE., Bond, SJ., Cheng, X., Silvestre, J-S., Rudd, JHF., Cheriyan, J. and Mallat, Z., 2021. Innate Lymphoid Cells Promote Recovery of Ventricular Function After Myocardial Infarction. J Am Coll Cardiol, v. 78
    Doi: 10.1016/j.jacc.2021.07.018
  • Aetesam-Ur-Rahman, M., Brown, AJ., Jaworski, C., Giblett, JP., Zhao, TX., Braganza, DM., Clarke, SC., Agrawal, BSK., Bennett, MR., West, NEJ. and Hoole, SP., 2021. Adenosine-Induced Coronary Steal Is Observed in Patients Presenting With ST-Segment-Elevation Myocardial Infarction. J Am Heart Assoc, v. 10
    Doi: http://doi.org/10.1161/JAHA.120.019899
  • 2020

  • Zhao, TX., Newland, SA. and Mallat, Z., 2020. 2019 ATVB Plenary Lecture: Interleukin-2 Therapy in Cardiovascular Disease: The Potential to Regulate Innate and Adaptive Immunity. Arterioscler Thromb Vasc Biol, v. 40
    Doi: 10.1161/ATVBAHA.119.312287
  • Nus, M., Basatemur, G., Galan, M., Cros-Brunsó, L., Zhao, TX., Masters, L., Harrison, J., Figg, N., Tsiantoulas, D., Geissmann, F., Binder, CJ., Sage, AP. and Mallat, Z., 2020. NR4A1 Deletion in Marginal Zone B Cells Exacerbates Atherosclerosis in Mice-Brief Report. Arterioscler Thromb Vasc Biol, v. 40
    Doi: 10.1161/ATVBAHA.120.314607
  • 2019

  • Zhao, TX. and Mallat, Z., 2019. Targeting the Immune System in Atherosclerosis: JACC State-of-the-Art Review. J Am Coll Cardiol, v. 73
    Doi: http://doi.org/10.1016/j.jacc.2018.12.083
  • Giblett, JP., Clarke, S., Zhao, T., McCormick, LM., Braganza, DM., Densem, CG., O'Sullivan, M., Adlam, D., Clarke, SC., Steele, J., Fielding, S., West, NEJ., Villar, SS. and Hoole, SP., 2019. The role of Glucagon-Like Peptide 1 Loading on periprocedural myocardial infarction During elective PCI (GOLD-PCI study): A randomized, placebo-controlled trial American Heart Journal, v. 215
    Doi: http://doi.org/10.1016/j.ahj.2019.05.013
  • 2018

  • Zhao, TX., Kostapanos, M., Griffiths, C., Arbon, EL., Hubsch, A., Kaloyirou, F., Helmy, J., Hoole, SP., Rudd, JHF., Wood, G., Burling, K., Bond, S., Cheriyan, J. and Mallat, Z., 2018. Low-dose interleukin-2 in patients with stable ischaemic heart disease and acute coronary syndromes (LILACS): protocol and study rationale for a randomised, double-blind, placebo-controlled, phase I/II clinical trial. BMJ Open, v. 8
    Doi: 10.1136/bmjopen-2018-022452
  • Clarke, SJ., Giblett, JP., Yang, LL., Hubsch, A., Zhao, T., Aetesam-Ur-Rahman, M., West, NEJ., O'Sullivan, M., Figg, N., Bennett, M., Wewer Albrechtsen, NJ., Deacon, CF., Cheriyan, J. and Hoole, SP., 2018. GLP-1 Is a Coronary Artery Vasodilator in Humans. J Am Heart Assoc, v. 7
    Doi: 10.1161/JAHA.118.010321
  • 2011

  • Holtzman, T., Sivam, V., Zhao, T., Frey, O., van der Wal, PD., de Rooij, NF., Dalley, JW. and Edgley, SA., 2011. Multiple extra-synaptic spillover mechanisms regulate prolonged activity in cerebellar Golgi cell-granule cell loops. J Physiol, v. 589
    Doi: http://doi.org/10.1113/jphysiol.2011.207167
  • Theses / dissertations

    2020 (No publication date)

  • Zhao, TX., 2020 (No publication date). PHARMACOLOGICAL MODULATION OF THE ADAPTIVE IMMUNE SYSTEM IN ISCHAEMIC HEART DISEASE
    Doi: 10.17863/CAM.55391
  • Conference proceedings

    2020

  • Zhao, TX., Sriranjan, RS., Lu, Y., Hubsch, A., Kaloyirou, F., Vamvaka, E., Helmy, J., Kostapanos, M., Klatzmann, D., Tedgui, A., Rudd, JHF., Hooles, SP., Bond, SP., Maga, Z. and Cheriyan, J., 2020. Low dose interleukin-2 in patients with stable ischaemic heart disease and acute coronary syndrome (LILACS) EUROPEAN HEART JOURNAL, v. 41
  • 2018

  • Hoole, SP., Clarke, S., Giblett, J., Aetesam-ur-Rahman, M., Zhao, T., West, N. and Cheriyan, J., 2018. GLUCAGON-LIKE PEPTIDE-1 (GLP-1) HAS NO EFFECT ON PERIPHERAL VASODILATATION BUT AUGMENTS CORONARY MICROCIRCULATORY FLOW IN HUMANS JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, v. 71
    Doi: http://doi.org/10.1016/S0735-1097(18)30561-8
  • Basatemur, G., Ackers-Johnson, M., Schoonejans, J., Kazachenka, A., Lam, B., Ma, M., Brimpari, M., Patel, M., Saleh, N., Murphy, D., Zhao, T., Yeo, G., Ferguson-Smith, A., Vallier, L., Sinha, S. and Mallat, Z., 2018. THE CHR9P21 RISK LOCUS AFFECTS IL-1/TLR SIGNALLING IN VSMC HEART, v. 104
    Doi: http://doi.org/10.1136/heartjnl-2018-BCS.128
  • Aetesam-ur-Rahman, M., Zhao, T., Giblett, J., Braganza, D., Clarke, S., Bennett, M., West, N. and Hoole, S., 2018. Instability of Coronary Flow Velocity and Basal Microvascular Resistance does not Affect Reproducibility of iFR Post- PCI. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, v. 72
    Doi: http://doi.org/10.1016/j.jacc.2018.08.1634






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