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Cambridge Cardiovascular

 
Imaging of atheroma
Imaging of damage in stroke
Imaging of recovery from stroke

Research

My research focuses on imaging the mechanisms of damage and recovery in stroke using multiple techniques. In particular:

1. Molecular imaging of atheroma - especially carotid plaque imaging using PET/CT and MRI techniques. Both Clinical and microPET imaging. Proof of principle trials of novel atheroma drugs with imaging biomarkers.

2. Imaging mechanisms of damage in both ischemic and haemorrhagic stroke using PET, CTperfusion and MRI imaging

3. Imaging mechanisms of recovery from aphasic stroke and behavioural interventions

Publications

Key publications: 

Baron JC, Farid K, Dolan E, Turc G, Marrapu ST, O'Brien E, Aigbirhio FI, Fryer TD, Menon DK, Warburton EA, Hong YT: Diagnostic utility of amyloid PET in cerebral amyloid angiopathy-related symptomatic intracerebral hemorrhage. J Cereb Blood Flow Metab. 2014 May;34(5):753-8.

Agarwal S, Day DJ, Sibson L, Barry PJ, Collas D, Metcalf K, Cotter PE, Guyler P, O'Brien EW, O'Brien A, O'Kane D, Owusu-Agyei P, Phillips P, Shekhar R, Warburton EA: Thrombolysis delivery by a regional telestroke network--experience from the U.K. National Health Service. J Am Heart Assoc. 2014 Feb 26;3(1):e000408.

Clatworthy PL, Warburton EA, Tolhurst DJ, Baron JC: Visual contrast sensitivity deficits in 'normal' visual field of patients with homonymous visual field defects due to stroke: a pilot study. Cerebrovasc Dis. 2013;36(5-6):329-35.

Alawneh JA, Moustafa RR, Marrapu ST, Jensen-Kondering U, Morris RS, Jones PS, Aigbirhio FI, Fryer TD, Carpenter TA, Warburton EA, Baron JC: Diffusion and perfusion correlates of the 18F-MISO PET lesion in acute stroke: pilot study. Eur J Nucl Med Mol Imaging. 2014 Apr;41(4):736-44.

Kwok CS, Potter JF, Dalton G, George A, Metcalf AK, Ngeh J, Nicolson A, Owusu-Agyei P, Shekhar R, Walsh K, Warburton EA, Myint PK; Anglia Stroke Clinical Network Evaluation Study (ASCNES) Group: The SOAR stroke score predicts inpatient and 7-day mortality in acute stroke. Stroke. 2013 Jul;44(7):2010-2.

Consultant physician in stroke medicine
Dr Elizabeth  Warburton