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Cambridge Cardiovascular



I am interested in applying engineering principles of mechanics and materials to biological systems. Applications include characterising and modelling deformation and rupture of arteries, including the effect of patient-specific geometry and disease. I also lead the Bioengineering research theme at the Department of Engineering.


Key publications: 

Impact of fiber structure on the material stability and rupture mechanisms of coronary atherosclerotic plaques
GR Douglas, AJ Brown, JH Gillard, MR Bennett, MPF Sutcliffe, Z Teng
Annals of biomedical engineering 45 (6), 1462-147

Layer-and direction-specific material properties, extreme extensibility and ultimate material strength of human abdominal aorta and aneurysm: a uniaxial extension study
Zhongzhao Teng, Jiaxuan Feng, Yongxue Zhang, Yuan Huang, Michael PF Sutcliffe, Adam J Brown, Zaiping Jing, Jonathan H Gillard, Qingsheng Lu
Annals of biomedical engineering 43 (11), 2745-2759

A uni-extension study on the ultimate material strength and extreme extensibility of atherosclerotic tissue in human carotid plaques
Z Teng, J Feng, Y Zhang, MPF Sutcliffe, Y Huang, AJ Brown, Z Jing, Q Lu, JH Gillard
2015, Journal of Biomechanics, 10.1016/j.jbiomech.2015.09.037

Material properties of components in human carotid atherosclerotic plaques: a uniaxial extension study. Z Teng, Y Zhang, Y Huang, J Feng, J Yuan, Q Lu, MPF Sutcliffe, AJ Brown, Z Jing, JH Gillard.  Acta biomaterialia 10 (12), 5055-5063

Changes in biomechanical properties of the coronary artery wall contribute to maintained contractile responses to endothelin-1 in atherosclerosis
CY Ooi, MPF Sutcliffe, AP Davenport, JJ Maguire
Life sciences 118 (2), 424-429

Leader of the Departmental Bioengineering Research Theme
Head of the Biomechanics Group
Co-Director of the Cambridge Centre for Engineering Better Care (CEBC)
Professor Michael  Sutcliffe