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Dr Isuru Induruwa

Dr Isuru  Induruwa

BHF Cambridge CRE Clinical Research Training Fellow 2016-2017

Research Interests

The Glycoprotein VI Receptor in Atrial Fibrillation & ThromboEmbolism (GRAFITE) study will investigate the involvement of platelets in blood clot formation. The research will be carried out on blood samples of individuals admitted to Cambridge University Hospitals with either atrial fibrillation or venous thromboembolism.

We will specifically look at any genetic variances that cause blood clots, as well as investigating the role of the platelet receptor glycoprotein VI in thrombus formation and whether its inhibition could lead to arresting the platelet cascade at an earlier stage and reduce the size of the thrombus formed.


stroke ; platelets


  • Atrial fibrillation
  • Stroke
  • Venous thromboembolism
  • Cerebrovascular disorders

Key Publications

Beyond antiplatelets: The role of glycoprotein VI in ischemic stroke. Induruwa I, Jung SM, Warburton EA. Int J Stroke. 2016 Aug;11(6):618-25.

Platelet collagen receptor Glycoprotein VI-dimer recognizes fibrinogen and fibrin through their D-domains, contributing to platelet adhesion and activation during thrombus formation. Induruwa et al.


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