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I am BHF Clinical Lecturer in Cardiovascular Medicine and Cardiology Registrar sub-specialising in interventional cardiology. I have an MPhil in Translation Medicine and Therapeutics from the University of Cambridge and subsequently completed a PhD with Prof Ziad Mallat.
Targeting inflammation in atherosclerosis and myocardial infarction is a promising therapeutic approach, though this potential has not yet been clinically realised. For my PhD, I completed two early phase clinical trials on immuno-modulation in patients with myocardial infarction targeting the adaptive immune system using low-dose interleukin-2 and rituximab. Currently, both therapies are being taken into phase 2b studies.
My ongoing research interests are in translational experimental medicine trials looking at immuno-modulation in atherosclerosis and other cardiovascular diseases.
Keywordsexperimental medicine ; clinical trials ; atherosclerosis ; coronary micro-circulation ; Immuno-modulation ; inflammation ; myocardial infarction ; acute coronary syndrome |
