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Cambridge Cardiovascular



Statistical methods for advancing epidemiological research

My research focuses on the development and application of statistical methods for advancing epidemiological research. I develop statistical methodology for handling missing data and measurement error, multiple longitudinal risk factors, multiple imputation, risk prediction and meta-analysis.

My applied work focuses on cardiovascular research with colleagues in the CEU and birth outcomes in collaboration with Prof Gordon Smith, Department of Obstetrics and Gynecology, University of Cambridge.


Key publications: 

Extending the MR-Egger method for multivariable Mendelian randomization to correct for both measured and unmeasured pleiotropy. Rees JMB, Wood AM, Burgess S. Stat Med. 2017 Dec 20;36(29):4705-4718.

A comparison of Cox and logistic regression for use in genome-wide association studies of cohort and case-cohort design. Staley JR, Jones E, Kaptoge S, Butterworth AS, Sweeting MJ, Wood AM, Howson JMM. Eur J Hum Genet. 2017 Jun;25(7):854-862.

The use of repeated blood pressure measures for cardiovascular risk prediction: a comparison of statistical models in the ARIC study. Sweeting MJ, Barrett JK, Thompson SG, Wood AM. Stat Med. 2017 Dec 10;36(28):4514-4528.

Parity, breastfeeding and risk of coronary heart disease: A pan-European case-cohort study. Peters SA, van der Schouw YT, Wood AM, Sweeting MJ, Moons KG, Weiderpass E, Arriola L, Benetou V, Boeing H, Bonnet F, Butt ST, Clavel-Chapelon F, Drake I, Gavrila D, Key TJ, Klinaki E, Krogh V, Kühn T, Lassale C, Masala G, Matullo G, Merritt M, Molina-Portillo E, Moreno-Iribas C, Nøst TH, Olsen A, Onland-Moret NC, Overvad K, Panico S, Redondo ML, Tjønneland A, Trichopoulou A, Tumino R, Turzanski-Fortner R, Tzoulaki I, Wennberg P, Winkvist A, Thompson SG, Di Angelantonio E, Riboli E, Wareham NJ, Danesh J, Butterworth AS. Eur J Prev Cardiol. 2016 Nov;23(16):1755-1765.

Association of Cardiometabolic Multimorbidity With Mortality. Emerging Risk Factors Collaboration, Di Angelantonio E, Kaptoge S, Wormser D, Willeit P, Butterworth AS, Bansal N, O'Keeffe LM, Gao P, Wood AM, Burgess S, Freitag DF, Pennells L, Peters SA, Hart CL, Håheim LL, Gillum RF, Nordestgaard BG, Psaty BM, Yeap BB, Knuiman MW, Nietert PJ, Kauhanen J, Salonen JT, Kuller LH, Simons LA, van der Schouw YT, Barrett-Connor E, Selmer R, Crespo CJ, Rodriguez B, Verschuren WM, Salomaa V, Svärdsudd K, van der Harst P, Björkelund C, Wilhelmsen L, Wallace RB, Brenner H, Amouyel P, Barr EL, Iso H, Onat A, Trevisan M, D'Agostino RB Sr, Cooper C, Kavousi M, Welin L, Roussel R, Hu FB, Sato S, Davidson KW, Howard BV, Leening MJ, Rosengren A, Dörr M, Deeg DJ, Kiechl S, Stehouwer CD, Nissinen A, Giampaoli S, Donfrancesco C, Kromhout D, Price JF, Peters A, Meade TW, Casiglia E, Lawlor DA, Gallacher J, Nagel D, Franco OH, Assmann G, Dagenais GR, Jukema JW, Sundström J, Woodward M, Brunner EJ, Khaw KT, Wareham NJ, Whitsel EA, Njølstad I, Hedblad B, Wassertheil-Smoller S, Engström G, Rosamond WD, Selvin E, Sattar N, Thompson SG, Danesh J. JAMA. 2015 Jul 7;314(1):52-60.

The estimation and use of predictions for the assessment of model performance using large samples with multiply imputed data. Wood AM, Royston P, White IR. Biom J. 2015 Jul;57(4):614-32.

The effect of rare variants on inflation of the test statistics in case-control analyses. Pirie A, Wood A, Lush M, Tyrer J, Pharoah PD. BMC Bioinformatics. 2015 Feb 20;16:53.

Association of Cardiometabolic Multimorbidity With Mortality. Emerging Risk Factors Collaboration, Di Angelantonio E, Kaptoge S, Wormser D, Willeit P, Butterworth AS, Bansal N, O'Keeffe LM, Gao P, Wood AM, ..., Thompson SG, Danesh J. JAMA. 2015 Jul 7;314(1):52-60.

Previous caesarean delivery and the risk of unexplained stillbirth: retrospective cohort study and meta-analysis. Moraitis AA, Oliver-Williams C, Wood AM, Fleming M, Pell JP, Smith G. BJOG. 2015 Oct;122(11):1467-74.

Previous miscarriage and the subsequent risk of preterm birth in Scotland, 1980-2008: a historical cohort study. Oliver-Williams C, Fleming M, Wood AM, Smith G. BJOG. 2015 Oct;122(11):1525-34.

A review of published analyses of case-cohort studies and recommendations for future reporting. Sharp SJ, Poulaliou M, Thompson SG, White IR, Wood AM. PLoS One. 2014 Jun 27;9(6):e101176.

Correcting for optimistic prediction in small data sets. Smith GC, Seaman SR, Wood AM, Royston P, White IR. Am J Epidemiol. 2014 Aug 1;180(3):318-24.

Metabolic mediators of body-mass index and cardiovascular risk. Wormser D, Wood AM, Di Angelantonio E, Thompson SG, Danesh J; Emerging Risk Factors Collaboration. Lancet. 2014 Jun 14;383(9934):2042-3.

Multiple imputation for an incomplete covariate that is a ratio. Morris TP, White IR, Royston P, Seaman SR, Wood AM. Stat Med. 2014 Jan 15;33(1):88-104.

Within-person variability in calculated risk factors: comparing the aetiological association of adiposity ratios with risk of coronary heart disease. Wormser D, White IR, Thompson SG, Wood AM. Int J Epidemiol. 2013 Jun;42(3):849-59.

More publications are available through PubMed.

Professor of Health Data Science
Associate Director and Theme Lead for Structured Data for the BHF Data Science Centre
Turing Fellow