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Professor Nick Wareham

Professor Nick Wareham

Director of CEDAR

Director of the MRC Epidemiology Unit

Research Interests

Nick undertakes research into the aetiological determinants of diabetes, obesity and related metabolic disorders, and the translation of that epidemiological understanding into preventive action. He is a Principal Investigator on the EPIC-Norfolk study and leads the working group for diabetes, obesity and physical activity in EPIC-Europe study. He is the co-ordinator of the InterAct EU FP6 funded project, which aims to investigate how genes and lifestyle factors interact to lead to type 2 diabetes. He has a programme of research into the genetic basis of obesity and type 2 diabetes as part of the Genetics of Energy Metabolism (GEM) consortium. His work on gene-environment interaction is based on quantitative trait studies and large scale population-based cohort studies. A key element of this work is the accurate measurement of lifestyle exposures including physical activity and he has developed and evaluated novel methods for measuring energy expenditure in free-living individuals in population-based studies. He is co-lead of the ADDITION study, a trial of screening for diabetes and intensive cardiovascular risk reduction undertaken in 3 European countries.


cardiovascular epidemiology ; diabetes

Key Publications

The current and potential health benefits of the National Health Service Health Check cardiovascular disease prevention programme in England: A microsimulation study.

Mytton OT, Jackson C, Steinacher A, Goodman A, Langenberg C, Griffin S, Wareham N, Woodcock J. PLoS Med. 2018 Mar 6;15(3):e1002517. doi: 10.1371/journal.pmed.1002517. eCollection 2018 Mar. Abstract BACKGROUND: The National Health Service (NHS) Health Check programme was introduced in 2009 in England to systematically assess all adults in midlife for cardiovascular disease risk factors. However, […]

Associations of active commuting with body fat and visceral adipose tissue: A cross-sectional population based study in the UK

Mytton OT, Ogilvie D, Griffin S, Brage S, Wareham N, Panter J Prev Med. 2017 Oct 10. pii: S0091-7435(17)30367-5. doi: 10.1016/j.ypmed.2017.10.017. [Epub ahead of print] Abstract The promotion of active travel (walking and cycling) is one promising approach to prevent the development of obesity and related cardio-metabolic disease. However the associations between active travel and […]

Weather, Day Length and Physical Activity in Older Adults: Cross-Sectional Results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Norfolk Cohort

Yu-Tzu Wu, Robert Luben, Nicholas Wareham, Simon Griffin, Andy Jones PLoS One. 2017 May 31;12(5):e0177767. doi: 10.1371/journal.pone.0177767. eCollection 2017. Abstract Background: A wide range of environmental factors have been related to active ageing, but few studies have explored the impact of weather and day length on physical activity in older adults. We investigate the cross-sectional […]

Neighbourhood greenspace is associated with a slower decline in physical activity in older adults: a prospective cohort study

Alice M. Dalton, Nick Wareham, Simon Griffin, Andrew P. Jones SSM – Population Health, Volume 2, December 2016, Pages 683–691 Abstract Maintaining physical activity in later life is important for maintaining health and function. Activity outdoors, such as walking, jogging and cycling, may provide an accessible, sociable and practical solution, but maintaining outdoor mobility may […]



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