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Dr Tammy Dougan

Dr Tammy Dougan

Cambridge Cardiovascular Research Centre Manager

Research Interests

Specialties: Immunology, autoimmunity, antibody production, innate immunity and inflammation.

Areas of interest:

Neutrophils

Inflammation

Atherosclerosis

Vasculitis

Abdominal Aortic Aneurysms


Office Phone: +44 (0)1223 746298

Research Interests

  • immune response in cardiovascular disease
  • autoimmunity
  • immunology
  • cardiac immunology
  • systemic lupus erythematosus
  • autoimmune diseases
  • atherosclerosis
  • immunotherapy
  • glomerular disease
  • chronic inflammation
  • vasculitis
  • Wegener's granulomatosis
  • ANCA vasculitis

Topics

  • Marfan syndrome
  • Cardiometabolic diseases
  • Small vessel diseases (SVD)
  • Aortic aneurysm
  • Vascular Surgery

Key Publications

Urinary monocyte chemoattraction protein-1 (MCP-1) is a marker of active renal vasculitis.

Tam FW, Sanders JS, George A, Hammad T, Miller C, Dougan T, Cook HT, Kallenberg CG, Gaskin G, Levy JB, Pusey CD.

Nephrol Dial Transplant. 2004 Nov; 19(11):2761-8. Epub 2004 Sep 7. PMID:15353578

 

Reduction of streptavidin RYDS-mediated renal adhesion by site-directed mutagenesis.

Samuel Murray, Anthony Maraveyas, Tammy Dougan & Anthony C Chu. Unit of Dermatology, Division of Medicine, Imperial Collage Scholl of Medicine, Hammersmith Hospital, London, UK. W12 0NN. Biochem Biophys Acta. 2002 Mar 15; 1570(2):81-8. PMID: 11985891 [PubMed – indexed for MEDLINE]

 

Characterisation of autoantibodies from patients with Goodpasture’s disease using a resonant mirror biosensor.

T. Dougan, A. Salama, J. Levy A.J.T George* & C.D. Pusey. Renal Section, Division of Medicine and * Department of Immunology, Imperial Collage School of Medicine, Hammersmith Hospital, London, UK. W12 0NN. Clin Exp Immunol. 2002 Jun; 128(3):555-61. PMID: 12067312 [PubMed – indexed for MEDLINE]

 

Goodpasture’s disease in the absence of circulating anti-glomerular basement membrane antibodies using standard techniques.

Alan D. Salama1 , Tammy Dougan1, Jeremy B.Levy1, Terry Cook2 , Steve Morgan3, Sarah Naudeer4, Andrew J. George5, David Evans1, Liz Lightstone1 and Charles D. Pusey1. 1 Renal Section and 5Department of Immunology, Division of Medicine, and 2Department of Histopathology, Imperial College School of Medicine, Hammersmith Hospital, London, 3Renal Unit, Basildon Hospital, Essex, 4Renal Unit, South Cleveland Hospital, Middlesbrough, Cleveland.

Am J Kidney Dis. 2002 Jun; 39(6):1162-7. PMID: 12046026 [PubMed – indexed for MEDLINE]

 

Clinical features and outcome of patients with both ANCA and anti-GBM antibodies.

J.B Levy, T. Hammad, A. Coulthart, T.Dougan & C.D Pusey. Renal Section, Imperial School of Medicine, Hammersmith Hospital, London, W12 0NN.

Kidney Int. 2004 Oct;66(4):1535-40. PMID: 15458448 [PubMed – indexed for Medline]

 

The relationship between blood pressure and aortic dilation in the angiotensin II mouse model of AAA

Tammy Dougan, Sai-Wang Seto, Corey S Moran, Catherine Rush, Lynn Woodward, Jonathan Golledge VBU, School of Medicine, James Cook University, Townsville, Australia, 4811.

Annals of the ACTM, Official Journal of The Australasian College of Tropical Medicine, Vol 12, supplement 1. Oct 2011.

 

Modulation of kinin B2 receptor signalling controls aortic dilatation and rupture in the angiotensin II-infused apolipoprotein E-deficient mouse

Tammy Dougan1*, Corey S. Moran1*, Catherine M. Rush2*, Roby J. Jose1, Erik Biros1, Paul E Norman4, Lajos Gera3, Jonathan Golledge1,5

 Vascular Biology Unit, Queensland Research Centre for Peripheral Vascular Disease, School of Medicine & Dentistry, James Cook University, Townsville, Queensland, Australia. Microbiology and Immunology Department, School of Veterinary and Biomedical Sciences, James Cook University, Townsville, Australia. 3 Department of Biochemistry, University of Colorado Denver, Aurora, Colorado, USA. School of Surgery, University of Western Australia, Fremantle Hospital, Fremantle. Western Australia, Australia. Department of Vascular and Endovascular Surgery, The Townsville Hospital, Townsville, Queensland, Australia. *Authors contributed equally to the study

Arterioscler Thromb Vasc Biol. 2016 May;36(5):898-907. doi: 10.1161/ATVBAHA.115.306945. Epub 2016 Mar 10.

 

Use of Nanoparticles As Contrast Agents for the Functional and Molecular Imaging of Abdominal Aortic Aneurysm

Theophilus I. Emeto1,2*†,  Faith O. Alele1,  Amy M. Smith1,  Felicity M. Smith1,  Tammy Dougan3 and  Jonathan Golledge2,4

1Public Health and Tropical Medicine, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD, Australia
2Queensland Research Centre for Peripheral Vascular Diseases, College of Medicine and Dentistry, James Cook University, Townsville, QLD, Australia
3Department of Medicine, University of Cambridge, Cambridge Biomedical Campus, Addenbrookes Hospital, Cambridge, UK and 4Department of Vascular and Endovascular Surgery, The Townsville Hospital, Townsville, QLD, Australia

REVIEW ARTICLE

Front. Cardiovasc. Med., 23 March 2017 | https://doi.org/10.3389/fcvm.2017.00016

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