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Dr Nick West

Dr Nick West

Consultant Cardiologist

Office Phone: 01480 364504

Research themes

Experimental Medicine:


ST elevation myocardial infarction ; interventional cardiology ; coronary stent design & technology ; vascular biology ; bioabsorbable stent technology ; coronary/left ventricular physiology coronary microvascular function ; diabetic restenosis

Key Publications

Prehospital ticagrelor in ST-segment elevation myocardial infarction. Montone RA, Hoole SP, West NE. N Engl J Med. 2014 Dec 11;371(24):2338-9.

Contemporary invasive imaging modalities that identify and risk-stratify coronary plaques at risk of rupture. Brown AJ, Costopoulos C, West NE, Bennett MR. Expert Rev Cardiovasc Ther. 2015 Jan;13(1):9-13.

Cardioprotection for percutaneous coronary intervention - Reperfusion quality as well as quantity. Giblett JP, West NE, Hoole SP. Int J Cardiol. 2014 Oct 22;177(3):786-793.

Dual-energy computed tomography imaging to determine atherosclerotic plaque composition: a prospective study with tissue validation. Obaid DR, Calvert PA, Gopalan D, Parker RA, West NE, Goddard M, Rudd JH, Bennett MR. J Cardiovasc Comput Tomogr. 2014 May-Jun;8(3):230-7.

Direct stenting is an independent predictor of improved survival in patients undergoing primary percutaneous coronary intervention for ST elevation myocardial infarction. McCormick LM, Brown AJ, Ring LS, Gajendragadkar PR, Dockrill SJ, Hansom SP, Giblett JP, Gilbert TJ, Hoole SP, West NE. Eur Heart J Acute Cardiovasc Care. 2014 Dec;3(4):340-6.

Coronary plaque structural stress is associated with plaque composition and subtype and higher in acute coronary syndrome: the BEACON I (Biomechanical Evaluation of Atheromatous Coronary Arteries) study. Teng Z, Brown AJ, Calvert PA, Parker RA, Obaid DR, Huang Y, Hoole SP, West NE, Gillard JH, Bennett MR. Circ Cardiovasc Imaging. 2014 May;7(3):461-70.

Cost-effectiveness of initial stress cardiovascular MR, stress SPECT or stress echocardiography as a gate-keeper test, compared with upfront invasive coronary angiography in the investigation and management of patients with stable chest pain: mid-term outcomes from the CECaT randomised controlled trial. Thom H, West NE, Hughes V, Dyer M, Buxton M, Sharples LD, Jackson CH, Crean AM; CECaT study group. BMJ Open. 2014 Feb 7;4(2):e003419.

Expansion and malapposition characteristics after bioresorbable vascular scaffold implantation. Brown AJ, McCormick LM, Braganza DM, Bennett MR, Hoole SP, West NE. Catheter Cardiovasc Interv. 2014 Jul 1;84(1):37-45.

Atherosclerotic plaque composition and classification identified by coronary computed tomography: assessment of computed tomography-generated plaque maps compared with virtual histology intravascular ultrasound and histology. Obaid DR, Calvert PA, Gopalan D, Parker RA, Hoole SP, West NE, Goddard M, Rudd JH, Bennett MR. Circ Cardiovasc Imaging. 2013 Sep;6(5):655-64.

Six-month IVUS and two-year clinical outcomes in the EVOLVE FHU trial: a randomised evaluation of a novel bioabsorbable polymer-coated, everolimus-eluting stent. Meredith IT, Verheye S, Weissman NJ, Barragan P, Scott D, Valdés Chávarri M, West NE, Kelbæk H, Whitbourn R, Walters DL, Kubica J, Thuesen L, Masotti M, Banning A, Sjögren I, Stables RH, Allocco DJ, Dawkins KD. EuroIntervention. 2013 Jul;9(3):308-15.

Coregistered intravascular ultrasound and optical coherence tomography imaging during implantation of a bioresorbable vascular scaffold. Brown AJ, McCormick LM, Hoole SP, West NE. JACC Cardiovasc Interv. 2013 Jul;6(7):e41-2.

Mitochondrial DNA damage can promote atherosclerosis independently of reactive oxygen species through effects on smooth muscle cells and monocytes and correlates with higher-risk plaques in humans. Yu E, Calvert PA, Mercer JR, Harrison J, Baker L, Figg NL, Kumar S, Wang JC, Hurst LA, Obaid DR, Logan A, West NE, Clarke MC, Vidal-Puig A, Murphy MP, Bennett MR. Circulation. 2013 Aug 13;128(7):702-12.

More publications available through PubMed.

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