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Cambridge Cardiovascular



Improved design of mitral valve rings

My Fellowship project strives to improve the materials and design of mitral valve rings.  These rings are essential to the treatment of ischaemic regurgitation and other mitral diseases, but existing rings are stiff and can restrict the heart’s movement.

I will identify materials that match natural mitral ring properties as closely as possible, produce prototype mitral rings, test and refine these in appropriate ex vivo models and ultimately test functionality in a suitable in vivo model.


Key publications: 

Left-handed cardiac surgery: tips from set up to closure for trainees and their trainers. Burdett C, Dunning J, Goodwin A, Theakston M, Kendall S. J Cardiothorac Surg. 2016 Sep 1;11(1):139.

Left-handed surgical instruments - a guide for cardiac surgeons. Burdett C, Theakston M, Dunning J, Goodwin A, Kendall SW. J Cardiothorac Surg. 2016 Aug 19;11(1):135.

Early and Late Outcomes After Minimally Invasive Mitral Valve Repair Surgery. Akowuah E, Burdett C, Khan K, Goodwin A, Lage IB, El-Saegh M, Smailes T, Hunter S. J Heart Valve Dis. 2015 Jul;24(4):470-7.

Thermoreactive clips do not reduce sternal infection: a propensity-matched comparison with sternal wires. Srivastava V, Yap CH, Burdett C, Smailes T, Kendall S, Akowuah E. Interact Cardiovasc Thorac Surg. 2015 Dec;21(6):699-704.

Suction on chest drains following lung resection: evidence and practice are not aligned. Lang P, Manickavasagar M, Burdett C, Treasure T, Fiorentino F; UK Cardiothoracic Trainees’ Research Collaborative.; UK Cardiothoracic Trainees' Research Collaborative. Eur J Cardiothorac Surg. 2016 Feb;49(2):611-6.

Manubrium-limited sternotomy decreases blood loss after aortic valve replacement surgery. Burdett CL, Lage IB, Goodwin AT, White RW, Khan KJ, Owens WA, Kendall SW, Ferguson JI, Dunning J, Akowuah EF. Interact Cardiovasc Thorac Surg. 2014 Oct;19(4):605-10.


BHF Centre of Excellence Clinical Research Training Fellow
 Clare  Burdett